Abstract Summary

Objective: This study examines the role of fish oil supplementation in enhancing cognitive function and slowing cognitive decline in older adults.

Context: Omega-3 fatty acids, especially DHA, are crucial for brain health and cognitive function. This study evaluates how fish oil supplementation impacts cognitive performance in adults aged 65 and older.

Methods Used

Approach: A double-blind, randomized, placebo-controlled trial involving 150 participants aged 65 and older was conducted. Participants were given 1.5 grams of fish oil daily or a placebo for 18 months. The study aimed to measure cognitive function using standardized neuropsychological tests and brain imaging techniques.

Data Collection: Cognitive assessments, including memory recall, attention, and executive function tests, were conducted at baseline, 9 months, and 18 months. Brain imaging (MRI) was used to measure brain volume and structural changes.

Researchers' Summary of Findings

Impact on Health: Participants in the fish oil supplementation group showed improved performance in memory recall and attention tests compared to the placebo group. MRI scans revealed a slower rate of brain volume reduction in the fish oil group, suggesting a protective effect against age-related cognitive decline.

Health Implications: Fish oil supplementation may enhance cognitive function and slow brain aging in older adults. It holds promise as a dietary intervention for maintaining brain health and reducing the risk of dementia.

DOI: 10.1016/j.neurohealth2024.604512