Ashwagandha and Heart Health: Impact on Blood Pressure, Cholesterol, and Cardiovascular Wellness

Abstract Summary

Objective
This study investigates the relationship between ashwagandha supplementation and its impact on heart health, focusing on blood pressure regulation, cholesterol levels, and overall cardiovascular health.

Context
Ashwagandha (Withania somnifera), a popular adaptogenic herb, is renowned for its stress-reducing properties and general wellness benefits. Recent research suggests that it may also play a role in heart health, particularly in lowering stress-related cardiovascular risk factors. While ashwagandha has been shown to influence cortisol levels, its effects on heart health, including blood pressure, lipid profiles, and heart disease prevention, warrant further examination. This research examines the available scientific evidence concerning ashwagandha’s role in heart health.

Methods Used

Approach
The study utilizes both experimental methods and a comprehensive literature review to explore ashwagandha's potential cardiovascular benefits. Experimental methods included clinical trials involving individuals taking ashwagandha supplements for 6-12 weeks, with a focus on monitoring heart rate, blood pressure, cholesterol levels, and inflammatory markers. A literature review was conducted to analyze the findings from previous studies on ashwagandha and its effects on heart health, particularly focusing on randomized controlled trials and meta-analyses.

Data Collection
Data were collected through monitoring changes in systolic and diastolic blood pressure, lipid profiles (total cholesterol, LDL, HDL, and triglycerides), and heart rate variability (HRV) in participants taking ashwagandha supplements. Researchers also gathered data on inflammatory markers, such as C-reactive protein (CRP), to assess the potential anti-inflammatory benefits of ashwagandha on cardiovascular health. Studies on animal models and human trials were reviewed to provide additional context and depth to the findings.

Researchers' Summary of Findings

Impact on Health
The experimental findings suggest that ashwagandha supplementation has a significant impact on lowering both systolic and diastolic blood pressure in individuals with high-stress levels or mild hypertension. Ashwagandha’s adaptogenic properties were shown to improve heart rate variability, indicating a positive effect on autonomic nervous system balance. Regarding cholesterol, some studies indicated that ashwagandha supplementation may lead to reduced total cholesterol and triglycerides, while increasing beneficial HDL cholesterol. Additionally, ashwagandha has demonstrated potential anti-inflammatory effects, with reductions in CRP levels observed in several studies, suggesting a heart-healthy anti-inflammatory benefit.

Health Implications
Ashwagandha supplementation can be considered beneficial for individuals dealing with stress-induced cardiovascular risks. It may help reduce blood pressure, improve lipid profiles, and lower inflammation, all of which contribute to better heart health. For individuals with high stress or mild hypertension, ashwagandha can be an effective, natural adjunct to managing heart health alongside other lifestyle modifications. However, individuals with more severe cardiovascular conditions should consult a healthcare provider before incorporating ashwagandha into their routine.

Sustainability
Ashwagandha is a plant-based supplement with minimal environmental impact compared to synthetic cardiovascular medications. Sustainable farming practices and organic cultivation of ashwagandha can further enhance its ecological benefits, making it a favorable option for those seeking natural and eco-friendly health solutions.

DOI
10.1007/s00424-025-00983-3