Strengthening Defenses: The Role of Vitamin C in Improving Immune Function

Abstract Summary

Objective: This study investigates the role of vitamin C supplementation in enhancing immune function in individuals with a compromised immune system.

Context: Vitamin C is known for its antioxidant properties and its importance in immune health. This research aims to assess the effectiveness of vitamin C supplementation in boosting immune function among individuals with weakened immune systems.

Methods Used

Approach: The study employs a randomized, double-blind, placebo-controlled trial design. Participants included individuals aged 18-65 with a documented history of recurrent infections or other indicators of compromised immune function. They were assigned to either the vitamin C supplementation group or a placebo group for twelve weeks. Immune function was monitored throughout the study.

Data Collection: Measurements included assessments of white blood cell count, levels of C-reactive protein (CRP), and the frequency and severity of infections at the start, six weeks, and twelve weeks. The results from the vitamin C group were compared to those from the placebo group.

Researchers' Summary of Findings

Impact on Health: The study found that vitamin C supplementation significantly enhances immune function. Participants receiving vitamin C showed higher white blood cell counts, lower CRP levels, and fewer and less severe infections compared to the placebo group.

Health Implications: Vitamin C supplementation can be a valuable strategy for boosting immune function in individuals with compromised immune systems. This suggests a potential non-invasive solution for enhancing overall immune health and reducing the frequency and severity of infections.

DOI: 10.1016/j.immuno.2024.789345