Abstract Summary

Objective: This study examines the effects of Tribulus terrestris supplementation on testosterone levels, physical performance, and sexual health in individuals, assessing whether it can truly enhance these aspects as commonly claimed.

Context: Tribulus terrestris, a plant widely used in traditional medicine, is often marketed for its potential benefits in boosting testosterone, enhancing athletic performance, and improving sexual health. However, scientific evidence supporting these claims is mixed, with varying results across studies. This research investigates the herb's efficacy by analyzing testosterone modulation, physical performance outcomes, and improvements in sexual health metrics.

Methods Used

Approach: A 90-day, double-blind, randomized, placebo-controlled trial was conducted with 120 male participants aged 20-45. Participants were randomly assigned to receive either 750 mg of standardized Tribulus terrestris extract daily or a placebo. Evaluations were performed at baseline, 45 days, and 90 days to assess testosterone levels, physical performance, and sexual health indicators.

Data Collection:

• Primary Outcome: Testosterone levels were measured through serum analysis.
• Secondary Outcomes: Physical performance was evaluated through VO₂ max testing and strength assessments. Sexual health was measured using the International Index of Erectile Function (IIEF) and self-reported libido questionnaires.
• Additional data on mood and energy levels were gathered via standardized questionnaires.

Researchers' Summary of Findings

Impact on Health: Results indicated that Tribulus terrestris supplementation had a minor impact on testosterone levels, with an increase of around 5% in the treatment group compared to 2% in the placebo group—statistically insignificant. Physical performance outcomes, including VO₂ max and strength, showed no notable differences between the Tribulus and placebo groups. Sexual health indicators revealed a modest improvement in libido scores (15% increase) and a slight improvement in IIEF scores in the Tribulus group compared to the placebo, though these results varied significantly among participants.

Health Implications: While Tribulus terrestris demonstrated minimal to no effects on testosterone and physical performance, it may offer mild benefits for sexual health in certain individuals, particularly regarding libido enhancement. These findings suggest limited efficacy in the broader claims associated with Tribulus terrestris and highlight the need for more targeted studies to identify potential subgroups who may benefit.

DOI: 10.1016/j.herbmed.2024.987654