Fish Oil Supplementation Reduces Cardiovascular Risk Factors: A Meta-Analysis

Abstract

Objective: To investigate the impact of fish oil supplementation on cardiovascular disease risk factors.

Context: Omega-3 fatty acids in fish oil may provide cardiovascular benefits, but optimal dosing is unclear.

Methods Used: A randomized controlled trial of 840 adults given low, moderate, or high dose fish oil capsules or placebo daily for 6 months.

Data Collection: Measured blood pressure, lipids, and inflammatory markers at baseline, 3 months, and 6 months.

Researchers' Summary of Findings

Impact on Health: Moderate and high dose fish oil significantly reduced triglycerides and increased HDL cholesterol versus placebo. Only high dose lowered blood pressure.

Health Implications: Fish oil reduces cardiovascular risk factors in a potentially dose-dependent manner. Optimal dosing requires further study.

DOI: 10.1161/CIRCULATIONAHA.108.816736